Our Story

In 2005, Dr. Chris Centeno and Dr. John Schultz, physicians in a small two-person pain management clinic in Colorado, pioneered the specialty of Interventional Orthopedics. They were the first in the world to apply stem cells from bone marrow concentrate to treat many orthopedic injuries. Two years later, they completed a two-year, IRB-approved research study of the use of both culture-expanded and same-day stem cells to treat knee and hip arthritis and low-back degenerative disc disease.

Then in 2009 a world-class lab was unveiled at Regenexx’s Colorado headquarters allowing further in-depth research on orthobiologic opportunities. The unveiling was closely followed by the addition of the first affiliate physician in New York in 2011.

Today Regenexx is known as the “Trusted Alternative to Orthopedic Surgery” with more than 80 Regenexx affiliates and over 100 highly-trained physicians treating dozens of orthopedic conditions.

Regenexx Milestones

The Beginning2005
Regenexx founders Dr. Chris Centeno and Dr. John Schultz

Dr. Chris Centeno and Dr. John Schultz embark on an idea to apply stem cells to treat orthopedic injuries in a small two-man clinic in Colorado.

Patient Registry2005

Regenexx begins its Patient Registry – a database for tracking patient outcomes.

Regenexx ® C2006
Regenexx C

Regenexx C (cultured) begins in Colorado.

Regenexx Publications2006

Regenexx releases the first of its free publications – A collection that will ultimately include both Free Reports and Free eBooks.

IRB Study2007

Dr. Chris Centeno and Dr. John Schultz complete a two-year, IRB-approved research study of the use of both culture-expanded and same-day stem cells to treat knee and hip arthritis and low-back degenerative disc disease.

Regenexx Blog2008

First blog post on Regenexx.com (started 2007) is published.

Regenexx® PL2008

Regenexx PL (platelet lysate), a highly specialized derivative of platelet-rich plasma, begins.

World Class Lab2009
Regenexx Lab

Regenexx unveils their world-class laboratory at its Broomfield, Colorado headquarters, lead by a doctorate-level research team.

Regenexx® SCP2009
Regenexx SCP

Regenexx SCP, a super-concentrated version of platelet rich plasma, begins.

Regenexx® SD2010
regenexx-sd

Regenexx-SD, a same-day, orthopedic stem cell treatment, begins.

First Affiliate Physician2011
RMC Logo

Dr. Rob Kramberg of the Rehabilitation Medical Center of New Jersey, is brought in as the first affiliate to the Regenexx Network.

Regenexx® C2011
Regenexx Cayman

Regenexx C begins in Grand Cayman

Affiliates
  • Health Link Medical Center – Oceanside, CA
  • Rejuv Medical – Waite Park, MN
  • Regenexx Cayman
  • ProMedica
  • Health Link Medical Center – San Rafael, CA
  • Regenexx Pittsburgh
  • New ReGeneration Orthopedics
  • Regenexx Australia
  • StemCell ARTS – Virginia
  • Chicago Arthritis and Regenerative Medicine
Fellowship Program2012
Two Doctors

Fellowship program introduced for mentorship and training of up-and-coming physicians.

Regenexx® PLM & AD

Regenexx PLM & Regenexx AD Begin

Affiliates2013
  • UCLA Health/Southern California Orthopedic Institute – Van Nuys, CA
  • TotalCare Health & Wellness
Affiliates2014
  • Beacon Orthopaedics & Sports Medicine
  • Regenexx Des Moines
  • Wasatch Pain Solutions
  • Vermont Regenerative Medicine
  • Health Link Medical Center – Beverly Hills, CA
  • UCLA Health/Southern California Orthopedic Institute – Thousand Oaks, CA
Affiliates2015
  • Columbia Pain Management
  • Bodyworks Musculoskeletal Medicine
  • RegenOrthoSport – Dallas, TX
First Health Benefit Plan Inclusion2015
meredith

First self-funded employer, Meredith, adds Regenexx to their health benefits plan, providing a cost saving solution that gives employees an alternative to orthopedic surgery.

Affiliates2016
  • Manzano Medical Group
  • Regenexx Las Vegas
  • Mountain View Rehabilitation
  • Regenexx Philadelphia
  • RegenOrthoSport – Hyderbad, India
  • Algone Interventional Pain Clinic
  • Texas Interventional Orthopedic and Regenerative Medicine
  • Center for Orthopedic Regenerative Medicine
World's Largest Safety Paper2016
Largest Safety Paper

Regenexx publishes the world’s largest stem cell safety paper in any medical indication.

Regenexx® A2M2016

Regenexx A2M Begins

Affiliates2017
  • Ortho Regenerative
  • Nashville Regenerative Orthopedics
  • RestorePDX
  • Rejuv Medical – Savage, MN
  • Chun Chuan Clinic
  • RegenOrthoSport – Mumbai, India
  • Eastern Idaho Spine, Sports and Rehab Center
Knee Arthritis Trial2017

First randomized control trial for knee arthritis completed in its third year.

Affiliates2018
  • AlgoCells
  • Northwest Center for Regenerative Medicine
  • AMR Pain and Spine Clinic
  • Interventional Orthopedics of Atlanta
  • Centeno-Schultz Clinic – Lone Tree, CO
  • Cutting Edge Integrative Pain Centers
  • Restore Orthopedics & Sports Medicine
  • Functional Rehabilitation Experts
  • Advanced PainCare and BioHealth Institute
  • Interventional Orthopedics CT
  • Momenta Pain Care
Affiliates2019
  • River City Rehabilitation & Spine Specialists
  • Center for Interventional Pain and Spine
  • Premier Medical Group
  • Elite Pain & Health
  • Interventional Pain Care
  • Coastal Regenerative Orthopedics and Wellness Center
Research Publication #262019

Twenty-sixth research publication.

60 Affiliate Sites2019

The Regenexx Affiliate Network hits 62 sites.

EHIR Traction Award2019
HER Traction Award

Regenexx receives the Employer Health Innovation Roundtable (EHIR) Traction Award at Cohort 3 (October) for a record number of matches.

Affiliates2020
  • Premier Orthopaedics
  • Physio Logic Medicine
  • Spine and Pain Centers
  • Ospina Medical Group
Rotator Cuff Tear Trial2020

Regenexx’s second randomized controlled trial is published on shoulder rotator cuff tears.