Interventional Orthopedics Using Orthobiologics
Regenexx founded the field of interventional orthopedics in 2005 and continues to lead in orthobiologic advancements today. Harnessing the body’s own natural healing abilities, the Regenexx approach offers a distinctly different option in orthopedic care, standing apart from traditional surgery, steroid injections, and prescription pain medications like opioids. Regenexx’s proprietary methods are built on extensive research in platelet-rich plasma and stem cells harvested from bone marrow concentrate.
Physicians in the licensed Regenexx network contribute to clinical integrity and results by supporting an outcomes database which tracks patient results. Our dedicated research and development team, supported by a specialized laboratory, continuously refines treatment protocols and our evidence-based approach. This commitment to innovation and data has resulted in one of the world’s most advanced platforms for in-office interventional orthopedics that contributes to surgical avoidance.
Regenexx has pioneered many of today’s biologic processing and treatment methods and published roughly half of all worldwide research on using bone marrow concentrate (which contains stem cells) for orthopedic injuries. The Regenexx approach to MSK care and its proprietary methods and injectates are uniquely positioned to meet the five key criteria insurers use to evaluate investigational treatments—including: Safety, Efficacy, Regulatory Pathway, Comparable to Standard of Care, and Prevalence.
Common Conditions Treated With Orthobiologics
Physicians in the licensed Regenexx network specialize in treating a wide range of musculoskeletal conditions, helping patients achieve an improved quality of life and optimized functional status. Below are some of the most common conditions and injuries treated with a more comprehensive list available to download.
Download this booklet to explore an expanded list of conditions treated across all body areas.
The Regenexx Approach vs. Total Knee Replacement for Knee OA
A healthcare innovation research institute that conducted the first health technology assessment of its kind evaluating cost-effectiveness and quality of life (QoL). This independent economic analysis from UMC Utrecht's THINC compares outcomes for patients who were treated using bone marrow concentrate vs. total knee replacement focusing on working age adults.
The THINC report found that compared with TKR surgery for knee OA, procedures using Regenexx injectates demonstrated:
- ~$20k in cost savings over 5 years
- Comparable quality of life
- ~70% decrease in subsequent knee replacements
Download Knee OA Report
THINC Report Conclusion: The Regenexx approach offers a significantly cost-effective option with comparable QoL* for knee OA treatment.
*QALY = Cost-effectiveness analysis metric rating how well different types of medical treatments extend and/or improve patients’ lives.
What Makes the Regenexx Approach Very Different?
The Regenexx approach offers a unique blend of cutting-edge regenerative therapies, deep commitment to ongoing research, and standardized, high-quality patient care that passes the bar and is carried out by a highly-skilled network of licensed physicians.
What makes a physician in the licensed Regenexx network different from other medical professionals offering MSK treatments or regenerative therapies? Physicians in the licensed Regenexx network are distinguished by a commitment to advanced, evidence-based interventional orthopedics and an adherence to rigorous, research-backed protocols.
Physician Expertise and Training
Physicians in the licensed Regenexx network represent over 100 board-certified and licensed MDs or DOs with network expansion moving toward 200 nationwide locations. They undergo specialized training in Interventional Orthopedics, receive third-party advanced instruction in image-guided injections, and are experts in treating dozens of MSK conditions.
Comprehensive Evaluations and Diagnostics
A comprehensive evaluation is required— utilizing a full range of motion test, SANS evaluation, and advanced ultrasound imaging when needed. The physician determines a customized treatment plan based on the specific condition and candidacy for procedure and initiates the utilization review and approval for the Regenexx benefit member.
Lab Processing Delivers a Customized Treatment
Not all regenerative treatments are created equally. Regenexx lab processing offers customizable cell concentrations ranging from 6X to 20X— far above what other providers routinely achieve. Every location in the licensed Regenexx network has an on-site lab to prepare the injectate and customizes the dose to treat the patient’s condition.
Image Guidance Targets the Exact Location of Injury
Physicians in the licensed Regenexx network use precise image guidance, such as fluoroscopy or ultrasound, for all injections. Injections performed with high-level image guidance ensure the most accurate placements of cells into the desired area and exact location of injury.
Regenexx Orthobiologics
Regenexx injectates, produced using Regenexx lab processing, routinely achieve 20x concentration — far above what non-Regenexx providers achieve. The cell processing for Regenexx injectates requires an on-site laboratory and complies with US state and Federal law.
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